Cov khoom xyaw: Cov khoom tseem ceeb ntawm cov khoom no yog morpholinonirazole.
Lub npe tshuaj: 1-[3-(4-morpholino)-2-hydroxypropyl]-2-methyl-5-nitro-1H-imidazole.
Chemical Structure:
Cov roj formula: C11H18N4O4
Molecular Luj: 270.29
Excipients: sodium chloride, dej rau kev txhaj tshuaj.
【Tus cwj pwm】
Cov khoom no yog xim daj-ntsuab rau yellowish-ntsuab ntshiab kua.
【Specifications】
100ml: morpholinonidazole 0.5g thiab sodium chloride 0.9g
【Indications】
Txhawm rau txo qhov tsim ntawm cov kab mob resistant thiab xyuas kom meej qhov ua tau zoo ntawm morpholinonidazole thiab lwm yam tshuaj tua kab mob, morpholinolinidazole yuav tsum tau siv nyob rau hauv ib qho kev txwv.
Kev kho lossis tiv thaiv tus kab mob tshwm sim los ntawm qhov pov thawj lossis xav tias yuav raug kab mob.
Yog tias muaj cov ntaub ntawv hais txog kab lis kev cai thiab kev ntsuas kev raug mob, cov ntaub ntawv no yuav tsum tau siv los xaiv lossis hloov kho cov tshuaj tiv thaiv kab mob.
Rooj. Yog tias tsis muaj cov ntaub ntawv no, kev paub hauv zos nrog cov ntaub ntawv muaj kab mob sib kis thiab kab mob kis tau zoo yuav pab tau rau kev xaiv kev kho mob.
Nws yuav tsum tau muab sau tseg hais tias kab lis kev cai thiab kev soj ntsuam susceptibility yuav tsum tau ua ua ntej kev tswj xyuas los txheeb xyuas cov kab mob thiab nws susceptibility rau morpholinonirazole.
Kev sib deev. Morolinonidazole tuaj yeem pib sai li sai tau thaum cov qauv sau, thiab hloov kho raws li cov txiaj ntsig raug paub.
Raws li cov ntaub ntawv soj ntsuam tam sim no ntawm cov khoom no, cov khoom no tsim nyog rau cov kab mob hauv qab no hauv cov neeg laus (Ntau dua lossis sib npaug rau 18 xyoo) tshwm sim los ntawm cov kab mob uas raug:
1. Gynecologic pelvic inflammatory disease (xws li endometritis, salpingitis, tubo-ovarian abscess, pelvic peritonitis, thiab lwm yam): los ntawm
Xws li peptic streptococcus, Bacteroides fragilis, Viron cocci, Bacteroides jisei, thiab lwm yam.
2. Kev phais ua ke rau kev kho mob purulent appendicitis thiab gangrenous appendicitis: suav nrog Bacteroides (Bacteroides fragilis, oval/
Bacteroides multiformes, Bacteroides monoformes, Bacteroides vulgaris, Bacteroides spp.), Clostridium spp. (Clostridium perfringens, Clostridium dienzymes,
Clostridium butyricum thiab lwm yam clostridia), Fusobacterium spp. (Fusobacterium nucleata, Fusobacterium muta), Anaerobic cocci (Kev zom zaub mov Streptococcus,
Velon cocci) thiab lwm yam.
Vim hais tias pelvic inflammatory kab mob thiab appendicitis yog sib xyaw kab mob ntawm anaerobic thiab aerobic kab mob, lwm yam adjuncts yuav tsum tau noj raws li kev kho mob xav tau.
Kev ntsuas kev kho mob, xws li cov tshuaj sib xyaw ua ke uas muaj txiaj ntsig zoo rau cov kab mob aerobic.
【Storage】
Khaws rau hauv qhov tsaus ntuj, kaw nruj thiab qhov chaw txias (tsis pub tshaj 20 degree).
【Packing】
Soda-lime iav infusion fwj filling, chlorobutyl roj hmab stopper, aluminium cap sealing ntim. 1 lub raj mis / lub thawv.
【Hnub Kawg】
24 hli.
【Cov khoom xyaw】 Cov khoom xyaw tseem ceeb: Antofloxacin hydrochloride. Molecular Luj: C18H21FN4O4.HCl
【Properties】 Cov khoom no yog ib ntsiav tshuaj.
【Indications】 Cov khoom no tsim nyog rau kev kho mob ntawm cov kab mob hauv qab no los ntawm cov kab mob rhiab heev: 1. Kev mob hnyav ntawm cov mob ntsws ntsws ntev: mob ntsws mob hnyav tshwm sim los ntawm Klebsiella pneumoniae; 2. Mob pyelonephritis: mob pyelonephritis tshwm sim los ntawm Escherichia coli; Mob cystitis: mob cystitis tshwm sim los ntawm Escherichia coli, thiab lwm yam.
【Dosage】 Cov khoom no tsim nyog rau kev kho mob ntawm cov kab mob hauv qab no los ntawm cov kab mob rhiab heev: 1. Kev mob hnyav ntawm cov kab mob ntsws ntev: mob hnyav ntawm cov kab mob ntsws uas tshwm sim los ntawm Klebsiella pneumoniae; 2. Mob pyelonephritis: mob pyelonephritis tshwm sim los ntawm Escherichia coli; Mob cystitis: mob cystitis tshwm sim los ntawm Escherichia coli, thiab lwm yam.
【Storage】 kaw.
[Specification] 0.1g (hauv C18H21FN4O4)
[Packing] {{0}}.1g*6s/box, 0.1g*10s/box, 0.1g*12s/box
[Hnub tas sijhawm] 24 lub hlis
【Cov khoom xyaw】 Cov khoom tseem ceeb ntawm cov khoom no yog erecoxib. Lub npe tshuaj: 1-n-propyl-3-(4-methylphenyl)-4-(4-methylsulfonylphenyl)-2, 5-dihydro{ {8}}H-2-pyrrolidone. Molecular Luj: C21H23NO3S
【Properties】 Cov khoom no yog cov ntsiav tshuaj zaj duab xis-coated, uas yog dawb tom qab tshem tawm cov zaj duab xis-txheej txheej.
【Indications】 Cov khoom no yog siv los txo cov tsos mob ntawm osteoarthritis.
【Siv thiab Dosage】 Tom qab noj tshuaj. Noj qhov ncauj. Cov koob tshuaj ib txwm muaj rau cov neeg laus yog 0.1 g (1 ntsiav tshuaj) ob zaug ib hnub rau 8 lub lis piam. Lub sijhawm noj tshuaj ntau ntawm ntau chav kawm yog txwv ib ntus rau 24 lub lis piam (suav nrog 24 lub lis piam).
【Storage】 Shading, kaw thiab khaws cia rau hauv qhov chaw qhuav
[Specification] 0.1 grams
[Packing] {{0}}.1g*10s/box, 0.1g*6 pieces/box
[Hnub tas sijhawm] 24 lub hlis
【Cov khoom xyaw】 Cov khoom xyaw nquag ntawm cov khoom no yog iramod.
【Properties】 Cov khoom no yog cov ntsiav tshuaj dawb lossis dawb dawb.
【Indications】 Nws yog haum rau cov tsos mob ntawm active rheumatoid mob caj dab, thiab yog haum rau cov txiv neej thiab cov poj niam uas tsis muaj kev yug me nyuam thaum lub sij hawm kho mob.
【Dosage】 Qhov ncauj. Noj 25 mg (1 ntsiav tshuaj) ib zaug tom qab noj mov, 2 zaug hauv ib hnub, 1 zaug thaum sawv ntxov thiab 1 zaug yav tsaus ntuj.
【Storage】 Shading, kaw thiab khaws cia.
[Specification] 25 mg
【Packing specifications】 Pharmaceutical composite film ntim. 14pcs / thawv.
[Hnub tas sijhawm] 24 lub hlis
【Cov khoom xyaw】 Cov khoom tseem ceeb yog ilaprazole. Lub npe tshuaj: 5-(1-hydro-pyrrole-1-yl)-2-[[(4-methoxy-3-methyl)-2- pyridyl]-methyl]-sulfinyl-1hydro-benzimidazole.
【Properties】 Cov khoom no yog cov ntsiav tshuaj enteric-coated, uas yog dawb los yog tawm-dawb tom qab tshem tawm cov txheej.
【Indications】 Cov khoom no yog tsim rau kev kho mob ntawm duodenal rwj thiab reflux esophagitis.
【Kev Siv thiab Kev Siv】 Cov khoom no yog siv rau cov neeg laus duodenal rwj thiab reflux esophagitis, nqos rau ntawm lub plab khoob txhua tag kis sawv ntxov (tsis zom), duodenal rwj: 5-10mg txhua zaus, ib hnub ib zaug, kev kho mob yog 4 lub lis piam, los yog raws li kws kho mob hais. Reflux esophagitis: 10 mg ib hnub ib zaug rau 4 lub lis piam. Rau cov neeg mob uas tsis kho, nws raug nquahu kom noj cov tshuaj rau lwm 4 lub lis piam; Rau cov neeg mob uas tau kho tab sis tseem muaj cov tsos mob, 5 mg ib hnub rau lwm 4 lub lis piam, los yog raws li kws kho mob qhia.
【Storage】 Shading, sealing, thiab khaws cia rau hauv qhov chaw txias (tsis pub tshaj 20 degree).
[Specification] 5 mg x 14 tab
【Packing specifications】 lub thawv
[Hnub tas sijhawm] 24 lub hlis
【Cov khoom xyaw】 Triphenylbiamidine.
【Properties】 Cov khoom no yog ib ntsiav tshuaj.
【Indications】 tus kab mob hookworm, ascariasis
[Dosage] qhov ncauj, kab mob hookworm: {{0}}.4g (4 ntsiav tshuaj) ib zaug noj. Tus kab mob Ascaris: 0.3g (3 ntsiav tshuaj) ib zaug noj.
【Storage】 kaw.
[Specification] 0.2g
[Packing] 0.2g*6s/box.
[Hnub tas sijhawm] 24 lub hlis
【Cov khoom xyaw】
Cov khoom tseem ceeb ntawm cov khoom no yog kolopavir hydrochloride.
Lub npe tshuaj: N-[(1S)-1-[[[[(2S)-2-[{5}}[4-[7-[2-[( 2S)-1-[(2S)-2-[(methoxycarbonyl)amino]-3-
Methyl-1-butyryl]-2-pyrrolidyl]-1H-imidazol-5-yl]-1,3-benzodioxazole-4-}yl]phenyl ]-1H-imidazole 2-yl]-1-pyrrolidin]-carbonyl]-2-}methylpropyl]-methyl carbamate dihydrochloride.
Chemical Structure:
Cov mis mos molecular: C41H50N8O8 · 2HCl
Molecular Luj: 855.81
【Tus cwj pwm】
Cov khoom no yog ib qho nyuaj capsule, thiab cov ntsiab lus yog dawb los yog tawm-dawb granules thiab hmoov.
【Indications】
Cov khoom no yog siv ua ke nrog sofosbuvir los kho cov neeg laus nrog genotypes 1, 2, 3 thiab 6 uas tau raug kho nrog cov noob tsis zoo lossis interferon-kho noob.
Tus kab mob siab C (HCV) kab mob, nrog lossis tsis them nyiaj rau cirrhosis.
【Specifications】
60 mg ib
Carrimycin yog thawj tus kheej tsim tshuaj tua kab mob macrolide cov khoom lag luam hauv Suav teb, thiab yog thawj cov tshuaj tua kab mob dav dav tshiab uas tau tshwm sim hauv ntiaj teb txij li cov npe ntawm azithromycin", "Yim Tsib Tsib Xyoo", "Kaum tsib xyoos. Txoj Kev Npaj" thiab "Tsib Hlis Tsib Tsib Xyoo" cov haujlwm tshawb fawb tseem ceeb. Qhov "Twelfth Tsib-Year Plan" tau suav nrog hauv kev tshawb fawb thiab thev naus laus zis hauv tebchaws. Nws tau raug soj ntsuam los ntawm Ministry of Science thiab Technology raws li "National Major New Drug Creation", thiab tam sim no tau txais daim ntawv tso cai sau npe tshuaj thiab daim ntawv pov thawj tshuaj tshiab.
Carithromycin muaj zog tiv thaiv kab mob gram-zoo, tshwj xeeb tshaj yog tawm tsam Streptococcus pneumoniae, Mycoplasma pneumoniae thiab chlamydia, thiab cov tshuaj tua kab mob tiv thaiv erythromycin thiab -lactam tshuaj tiv thaiv kab mob, kab mob khaub thuas bacillus, Legionella, Pseudomonas aeruginosaingfredium thiab Clostridium. Tsis muaj kev sib tw ua tiav nrog cov tshuaj zoo sib xws. Nws muaj lipophilicity siab, ceev lub qhov ncauj nqus, muaj zog cov ntaub so ntswg permeability, dav tis, ntev tu lub sij hawm nyob rau hauv vivo, thiab zoo tshuaj tua kab mob nyhuv thiab immunomodulatory nyhuv. Kev sim hauv vitro tau ua pov thawj tias cov tshuaj tua kab mob ntawm carithromycin hauv vitro yog 64 npaug siab dua li ntawm erythromycin, thiab kev ua tau zoo ntawm cov kab mob kis tau zoo dua li ntawm azithromycin. Cov txiaj ntsig ntawm kev sim tshuaj hauv tsib lub tsev kho mob qib siab, suav nrog Peking Union Medical College Tsev Kho Mob, tau pom tias tag nrho cov txiaj ntsig zoo rau kev kho mob ntawm cov kab mob ua pa xws li mob ntsws yog 95.35%, thiab kev nyab xeeb yog siab. Piv nrog rau cov tshuaj tua kab mob tseem ceeb uas twb muaj lawm, carrimycin muaj cov txiaj ntsig zoo ntawm kev nyab xeeb, kev ua tau zoo thiab tsis kam tiv thaiv.
Cov kev tshawb fawb ua ntej tau pom tias nws inhibits P13K / mTOR teeb liab hloov txoj hauv kev ntawm A549 hlwb, txo cov qib IL-6 thiab IL-8, inhibits kev qhia ntawm PD-L1 hauv qog hlwb, yog li inhibiting qhov tshwj xeeb ua kom T hlwb, thiab inhibits qhov kev loj hlob ntawm ntau hom qog hlwb. Nws muaj kev ua haujlwm ntawm daim siab fibrosis; Nws muaj cov txiaj ntsig ntawm kev txo qis cov kab mob IL-4 thiab IL-1 hauv cov qauv tiv thaiv kab mob; Carithromycin muaj lub luag haujlwm ntawm kev tswj hwm kev tiv thaiv kab mob, txhawb kev tsiv teb tsaws ntawm neutrophil mus rau qhov chaw ntawm qhov mob hauv lub cev, txhim kho lub cev tiv thaiv kab mob, thiab tib lub sijhawm, nws tuaj yeem txhim kho phagocytosis ntawm macrophages, txhim kho lub cev tiv thaiv kab mob, thiab lwm yam. Qhov kev tshawb pom ntawm qhov tsis pom kev mob ntsws hauv Wuhan, peb tau siv lub peev xwm ntawm carithromycin tawm tsam Tus kab mob COVID{11}}, thiab cov kev sim tau pom tias muaj zog heev ntawm tes tiv thaiv COVID{14}} kev ua haujlwm.
Cov kws tshaj lij hauv kev lag luam hais txog carithromycin ntau heev thiab kwv yees tias nyob rau hauv kaum xyoo, yuav tsis muaj cov tshuaj tshiab no, uas tsis yog tsuas yog kho cov kab mob xwb, tab sis kuj cawm tib neeg txoj sia, thiab tuaj yeem siv los ua cov tshuaj tiv thaiv hauv tebchaws.
【Cov khoom xyaw】:
Cov khoom xyaw tseem ceeb ntawm cov khoom no: Abovite Tshuaj Lub Npe: Acetyl monocolor-Valley-Valley-Color-Heaven-Essence-Valley-Isobright-Celestial-Celestial-Celestial-Caseine-Su-(N-2-[{15} }}(N-(3-maleediimidepropionyl)amino)ethoxy]ethoxy}acetyl)-Ly-Bright-Isole-Group-Valley-Bright-Iso-Grain-Silk-Glutamine-Glutamine-Glutamine Glutamine Valley-Lys- Celestial-Glutamine-Glutamine Molecular Formula: C204H306N54O72 Molecular Luj: 4666. 93 Cov khoom no tsis muaj tshuaj ntxiv.
【Cov yam ntxwv】:
Cov khoom no yog tawm dawb los yog lub teeb daj xoob xoob los yog hmoov.
【Indications】:
Abbervir yog tib neeg kev tiv thaiv kab mob tiv thaiv kab mob (HIV-1) fusion inhibitor. Nws yog qhov tsim nyog rau kev kho tus kab mob HIV-1 cov neeg mob uas tseem rov ua dua nrog tus kab mob HIV-1 tom qab kho nrog lwm cov tshuaj tiv thaiv kab mob ua ke nrog lwm cov tshuaj tiv thaiv kab mob.
【Storage Method】:
Khaws cia tiv thaiv lub teeb, kaw, khov (-20 ± 5C).
Kev txhaj tshuaj Celiqimab yog ib qho kev sib xyaw ua ke ntawm tib neeg los tiv thaiv IL-17A monoclonal antibody nws tus kheej tsim los ntawm lub tuam txhab, uas tau sau npe thiab cais raws li cov khoom siv tshuaj lom neeg hauv chav kawm 1 nrog IL-17A raws li lub hom phiaj ntawm kev ua. Cov khoom lag luam tuaj yeem khi rau IL-17Ib protein nyob rau hauv cov ntshav los ntawm cov tshuaj tiv thaiv kab mob, thaiv kev khi ntawm IL-17A rau IL-17RA, thiab inhibit qhov tshwm sim thiab kev loj hlob ntawm o, thiaj li ua tiav kev kho mob ntawm cov kab mob autoimmune xws li cov quav hniav psoriasis thiab axial spondyloarthritis nrog IL-17Ib qho overexpression